BUZATTO

RESEARCH GROUP

UNTARGETED LIPIDOMICS OF BIOLOGICAL SAMPLES

EXPLORING LIPIDOMICS: from molecular landscapes to biological insights

We employ cutting-edge LC-MS untargeted lipidomics techniques to investigate the lipid composition of various types of biological samples. Our main goals include:

  • developing new analytical methodologies for untargeted lipidomics of biological samples using LC-MS, including serum, plasma, tissues, extracellular vesicles, bacteria, mammalian cells, plants, milk, cerebrospinal fluid, and others

  • developing lipid databases and data processing solutions (software development)

  • characterization of the lipidome at the species level

  • elucidating biochemical pathways involved in pathological and physiological phenomena

  • studying the correlation between the lipidome of extracellular vesicles, intercellular communications, and pathogenesis (cancer, neurological conditions)

  • finding new biomarkers for human diseases, with particular emphasis on neurodegeneration and neurological diseases

  • investigating the relationship between lipids, the microbiome, and mechanisms of antibiotic resistance

JOIN THE TEAM!

The Buzatto lab is seeking dedicated students at all levels, ranging from undergraduate to graduate studies. We are particularly searching for Master’s degree students.

Diversity within a research team promotes a rich and effective environment for collaborative science that foments growth and evolution. We welcome trainees from all backgrounds. If you share our passion for lipids and mass spectrometry, we invite you to contact us!

LASTEST NEWS

February 02, 2024

Our group submitted our first abstracts to the ASMS 2024 meeting. Looking forward to Anaheim!

January 29, 2024

Undergraduate student Cecilia Chen is joining us to develop a study on mechanisms of antibiotic response in E. Coli strains. We expect to define lipid species that are differentially found when UPEC strains are exposed to sub-letal dosages of antibiotics.

January 17, 2024

The Buzatto group is now part of the Hotchkiss Brain Institute and affiliated to the Mathison Centre for Mental Health Research. These new connections will further enhance our research into the correlations between lipid species, neurodegeneration, and neurological diseases. We aim to expand our investigations into mental health research in the near future.

November 01, 2023

We are starting an exciting research line into the lipidome of Escherichia coli with undergraduate student Amy Wycislik. She will spend a few months with the Buzatto group developing an honours project. Welcome, Amy!

October 24, 2023

Ous investigations into the relationship between lipids and Amyotrophic Lateral Sclerosis (ALS) continues with undergraduate student Zoha Asif. She is working on data processing solutions to improve lipid identification, followed by a biochemical investigation into pathological mechanisms.

August 28, 2023

The Buzatto research group was represented at the 8th Lipidomics Forum - iLS Annual Conference in Vienna, Austria. Adriana won the MANA Early Career Member travel award to attend the meeting and showcase our initial research on the lipid composition of small extracellular vesicles. It was a wonderful opportunity for networking with top scientists in lipidomics and seeing the beautiful Vienna!