The Buzatto lab is in its early stages, embarking on an exciting journey of scientific exploration of lipids. While we lay the foundation for our research, we would like to showcase the recent publications of our Principal Investigator, Adriana.

• Protocol for untargeted lipidomics of human serum using LC-TIMS-PASEF

  Fernanda Sousa Monteiro, Adriana Zardini Buzatto

  STAR Protocols 2026, 7(2), 104607

• Disruption of the angiopoietin-like system connects lipid homeostasis and hypothalamic dysfunction in ALS

  Sruthi Sankari Krishnamurthy, Adriana Zardini Buzatto, Caley Campkin, Hans-Peter Müller, Diana Wiesner, Jochen Weishaupt, Veronika Klose, Maximilian Wiesenfarth, Zeynep Elmas, Christine Herrmann, Özlem Parlak, Kornelia Günther, Rami Saad, Ulrike Weiland, Luc Dupuis, Albert Ludolph, Liang Li, Jan Kassubek, Johannes Dorst, Francesco Roselli

  BMC Medicine 2025, 24 (1), 210

• Prebiotics partially protect offspring from maternal antibiotic-induced obesity risk by altering maternal milk microbiota and gut colonization in Sprague-Dawley rats

  Dana E Lowry, Nicole A Cho, Kara Sampsell, Kate M Sales, Erin W Noye Tuplin, Melissa Biddle, Weilan Wang, Faye Chleilat, Micalee R Chow, Adriana Zardini Buzatto, Raylene A Reimer

  The Journal of Nutritional Biochemistry 2025, 110337

• Lipidomic profiling of Arabidopsis chloroplast protein phosphatase SLP1 mutants reveals altered diurnal lipid remodeling

  Chris White-Gloria, Greg B Moorhead, Adriana Zardini Buzatto

  BBA advances 2025, 100180

• Pericardial fluid-derived small extracellular vesicles from patients with coronary disease alter the lipidome of human coronary artery endothelium

  Ali Fatehi Hassanabad, Megan B Meechem, Yi Li Chen, Anna N Zarzycki, Mortaza Fatehi Hassanabad, Adriana Zardini Buzatto, Paul WM Fedak, Vaibhav B Patel

  CJC Open 2025

• Development of a robust sulfo-phospho-vanillin assay for sample normalization in LC-MS-based lipidomics

  Fernanda S. Monteiro, Adriana Z. Buzatto, Liang Li

  Analytica Chimica Acta 2025, 1329, 348676

• Lipidomic signatures in microglial extracellular vesicles during acute inflammation: a gateway to neurological biomarkers

  Nikita Ollen-Bittle, Wenxuan Wang, Kimberly Molina Bean, Shuang Zhao, Adriana Zardini Buzatto, Yifei Dong, Liang Li, Shawn N. Whitehead

  Journal of Neurochemistry 2025, 169 (11), e70309

• The ER thioredoxin-related transmembrane protein TMX2 controls redox-mediated tethering of ER-mitochondria contacts

  Junsheng Chen, Megan C Yap, Arthur Bassot, Danielle M Pascual, Tadashi Makio, Jannik Zimmermann, Heather Mast, Rakesh Bhat, Samuel G Fleury, Yuxiang Fan, Adriana Zardini Buzatto, Jack Moore, Klaus Ballanyi, Liang Li, Michael Overduin, M Joanne Lemieux, Hélène Lemieux, Grazia MS Mancini, Bruce Morgan, Paul C Marcogliese, Thomas Simmen

  Cell Reports 2025, 44 (11)

• The Lipid Composition of the Exo-Metabolome from Haemonchus contortus

  Pablo Godoy, Behrouz Rezanezhad Dizaji, Adriana Z. Buzatto, Laura Sanchez, Liang Li

  Metabolites 2025, 15(3), 193

• Lipidomics Profiling of Metformin-Induced Changes in Obesity and Type 2 Diabetes Mellitus: Insights and Biomarker Potential

  Muhammad Mujammami, Shereen M. Aleidi, Adriana Zardini Buzatto, Awad Alshahrani, Reem H. AlMalki, Hicham Benabdelkamel, Mohammed Al Dubayee, Liang Li, Ahmad Aljada, Anas M. Abdel Rahman

  Pharmaceuticals 2023, 16(12), 1717

• An integrated multi-OMICS approach highlights elevated non-esterified fatty acids impact BeWo trophoblast metabolism and lipid processing

  Zachary JW Easton, Ousseynou Sarr, Lin Zhao, Adriana Z Buzatto, Xian Luo, Shuang Zhao, Liang Li, Timothy RH Regnault

  Metabolites 2023, 13(8), 883

• The metabolic and lipidomic profiling of the effects of tracheal occlusion in a rabbit model of congenital diaphragmatic hernia

  Zachary E Easton, Timothy RH Regnault, Martina Mudri, Shuang Zhao, Shane A Smith, Adrianna Zardini Buzatto, Janet Li, Ryan Duruisseau-Kuntz, Jacob Davidson, Liang Li, Andreana Bütter

  Journal of Pediatric Surgery 2023, 58(5), 971-98

• Contaminating transfection complexes can masquerade as small extracellular vesicles and impair their delivery of RNA

  Jenna McCann, Carmen Daniela Sosa‐Miranda, Huishan Guo, Ryan Reshke, Alexandre Savard, Adriana Zardini Buzatto, James A Taylor, Liang Li, Derrick J Gibbings

  Journal of extracellular vesicles 2022, 11(10), e12220

• Comprehensive serum lipidomics for detecting incipient dementia in Parkinson’s disease

  Adriana Zardini Buzatto, Jaspaul Tatlay, Barinder Bajwa, Dorothea Mung, Richard Camicioli, Roger A Dixon, Liang Li

  Journal of Proteome Research 2021, 20(8), 4053-4067

• Tissue lipidomic alterations induced by prolonged dexamethasone treatment

  Adriana Zardini Buzatto, Abeer Malkawi, Essa M Sabi, Ahmed H Mujamammi, Liang Li, Anas M Abdel Rahman

  Journal of Proteome Research 2021, 20(3), 1558-1570

• Lipidomics of Biological Samples for the Assessment of Physiological and Pathological Processes

  Adriana Zardini Buzatto

  Ph.D. Thesis, 2020, University of Alberta

• Development of a NanoLC-MS workflow for high-sensitivity global lipidomic analysis

  Adriana Zardini Buzatto, Brian K Kwon, Liang Li

  Analytica Chimica Acta 2020, 1139, 88-99

• Lipidome alterations induced by cystic fibrosis, CFTR mutation, and lung function

  Adriana Zardini Buzatto, Mai Abdel Jabar, Imran Nizami, Majed Dasouki, Liang Li, Anas M Abdel Rahman

  Journal of Proteome Research 2020, 20(1), 549-564

• Comprehensive lipidomic and metabolomic analysis for studying metabolic changes in lung tissue induced by a vaccine against respiratory syncytial virus

  Adriana Zardini Buzatto, Indranil Sarkar, Sylvia van Drunen Littel-van den Hurk, Liang Li

  ACS Infectious Diseases 2020, 6(8), 2130-2142

• Metabolomic and immunological profiling of respiratory syncytial virus infection after intranasal immunization with a subunit vaccine candidate

  Indranil Sarkar, Adriana Zardini Buzatto, Ravendra Garg, Liang Li, Sylvia van Drunen Littel-van den Hurk

  Journal of Proteome Research 2019, 18(3), 1145-1161

• Assessment of nucleosides as putative tumor biomarkers in prostate cancer screening by CE–UV

  Adriana Zardini Buzatto, Mariana de Oliveira Silva, Ronei Jesus Poppi, Ana Valéria Colnaghi Simionato

  Analytical and Bioanalytical Chemistry 2017, 409, 3289-3297

• Higher detectability method for the analysis of nucleosides, putative tumor biomarkers, in blood serum samples by CE‐UV with reversed EOF

  Adriana Zardini Buzatto, Sumaya Ferreira Guedes, Mariana de Oliveira Silva, Jéssica Mirela Gallafrio, Ana Valéria Colnaghi Simionato

  Electrophoresis 2015, 36(23), 2968-2975

• Analysis of nucleosides, putative tumor biomarkers for prostate cancer, by capillary electrophoresis

  Adriana Zardini Buzatto

  M.Sc. Dissertation, 2014, Universidade Estadual de Campinas (UNICAMP)

• Metabolomic investigation of human diseases biomarkers by CE and LC coupled to MS

  Adriana Z Buzatto, Ana Carolina de Sousa, Sumaya F Guedes, Zuzana Cieslarova, Ana Valeria C Simionato

  Electrophoresis 2014, 35(9), 1285-1307

• Development and validation of a micellar electrokinetic capillary chromatographic method for the assessment of nucleosides, potential biomarkers, in blood serum

  Adriana Z Buzatto, Sumaya F Guedes, Lucas T Vidotto, Laurione C Oliveira, Ana Valéria C Simionato

  Journal of the Brazilian Chemical Society 2013, 24, 904-913